S Eliuk, K Ruiter and P Boulanger (2011). Classifying HIV-1 Circulating Recombinant Forms. In BIOCOMP'11 - The 2011 International Conference on Bioinformatics & Computational Biology, 7 pages, Las Vegas, USA. July 2011. WorldComp.
The intent of the following paper is to expound on new algorithmic ideas that show marked improvement over formerly state-of-the-art functions in HIV-1 sub-typing, such as those found in Wu et al. and NCBI. The paper identifies deficiencies in these older conceptions and sets forth, in a clear and simplistic manner, our improved methodology. The two main boons to the new method described below are the development and utilization of reference profiles and the increased recombination prediction accuracy due to increased branching options and redesigned replacement policies. There is also a new importance placed on absolute prediction accuracy, thus making room for a multitude of real-world possibilities.
Back to to publications.