J J Liu, J K Rudzinski, S J Mah, A L Thiesen, H Bao, E Wine, S C Ogg, P Boulanger, R N Fedorak and K L Madsen (2011). Epithelial Gaps in a Rodent Model of Inflammatory Bowel Disease: A Quantitative Validation Study. Clinical and Translational Gastroenterology 2 (June 2011): 8 pages.
Confocal laser endomicroscopy (CLE) is a non-invasive imaging modality of the gastrointestinal tract. Epithelial gaps in the small intestine of patients and rodents have been demonstrated using CLE. The goal of this study was to quantitatively validate the findings of epithelial gap density observed with CLE against confocal microscopy (CM) and light microscopy.
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