Summary of RoBiC Data/Results - Diagnostic Datasets

	Diagnostic Datasets
	D1: Lung Cancer	D2: AML-ALL(1)	D3: Colon Cancer	D4: Prostate (2)
Data	Ptr Data	Ptr Data	Ptr Data	Ptr Data
Number of Samples	181	72	62	136
Number of Genes/Attributes	12533	7129	2000	12600
Class Distribution	ADCA (150) / Mesothelioma (31)	ALL (47) / AML (25)	Cancer (40) / Normal (22)	Tumor (77) / Normal (59)
Baseline %	82.87%	62.27%	64.52%	56.62%
BiC(RoBic,SVM) # of biclusters(3)	96.13 ±2.5 % 1	84.72 ±6.11 % 10	88.71 ±4.1 % 3	86.77 ±5.7 % 1

⁽¹⁾ This dataset is for predicting the AML versus ALL samples.

⁽²⁾ This dataset is for predicting cancer versus normal samples.

⁽³⁾ RoBiC bicluster characteristics can be found here.

• D₁: Gavin J. Gordon, Roderick V. Jensen, Li-Li Hsiao, Steven R. Gullans, Joshua E. Blumenstock, Sridhar Ramaswamy, William G. Richards, David J. Sugarbaker and Raphael Bueno, Translation of Microarray Data into Clinically Relevant Cancer Diagnostic Tests Using Gene Expression Ratios in Lung Cancer And Mesothelioma, Cancer Research, 62, 4963-4967, September, 2002.

• D₂: T.R. Golub, D.K. Slonim, P. Tamayo, C. Huard, M. Gaasenbeek, J.P. Mesirov, H. Coller, M.L. Loh, J.R. Downing, M.A. Caligiuri, C.D. Bloomfield and E.S. Lander, Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring, Science, 286, 531-537, October 1999.

• D₃: U. Alon, N. Barkai, D.A. Notterman, K. Gish, S. Ybarra, D. Mack and A.J. Levine, Broad Patterns of Gene Expression Revealed by Clustering Analysis of Tumor and Normal Colon Tissues Probed by Oligonucleotide Arrays, Proceedings of the National Academy of Sciences 96:12, 6745-6750, June, 1999.

• D₄: D. Singh, P.G. Febbo, K. Ross, D.G. Jackson, J. Manola, C. Ladd, P. Tamayo, A.A. Renshaw, A.V. D'Amico, J.P. Richie, E.S. Lander, M. Loda, P.W. Kantoff, T.R. Golub, and W.R. Sellers, Gene Expression Correlates of Clinical Prostate Cancer Behavior, Cancer Cell, 1, 203--209, March, 2002.

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