PA-GOSUB: A Searchable Database of Model Organism Protein Sequences With Their Predicted GO Molecular Function and Subcellular Localization
PA-GOSUB (Proteome Analyst: GO Molecular Function and Subcellular Localization) is a publicly-available,
web-based, searchable, and downloadable database that contains the sequences, predicted GO molecular functions,
and predicted subcellular localizations of the more than 107,000 proteins from 10 model organisms (and growing),
covering the major kingdoms and phyla for which annotated proteomes exist (http://www.cs.ualberta.ca/~bioinfo/PA/GOSUB).
The PA-GOSUB database effectively expands the coverage of subcellular localization and GO function annotations by a
significant factor (already over 5 for subcellular localization, as compared to Swiss-Prot v42.7) and more model organisms
are being added to PA-GOSUB as their sequenced proteomes become available.
PA-GOSUB can be used in three main ways. First, a researcher can browse the pre-computed PA-GOSUB annotations on a
per-organism and per-protein basis using annotation-based and text-based filters.
Second, a user can perform BLAST searches against the PA-GOSUB database and use the annotations from the homologs
as simple predictors for the new sequences.
Third, the entire PA-GOSUB can be downloaded in either FASTA or comma-separated values (CSV) formats.