PENCE Proteome Analyst PA-GOSUB 2.5

Proteome Analyst is currently analyzing several commonly requested proteomes and making results available here for public viewing. Please bookmark this page as the URLs for individual result sets may change in the future

Animal | Archaea | Fungi | Gram-negative | Gram-positive | Plant

1. Saccharomyces cerevisiae (Brewer's Yeast)
   Saccharomyces cervisiae is a very useful model for scientists: it is a eukaryotic organism (its genetic material is contained in a nucleus), and is therefore similar to cells from evolved organisms. As easy to manipulate as a bacterium, yeast is a simplified model of the cells that make up human beings. It has been widely studied because the cell cycle in a simple yeast is very similar to the cell cycle in humans, and regulated by homologous proteins. Its prominent useful features are the cheap and easy cultivation, short generation times, the detailed genetic and biochemical knowledge accumulated in many years of research and the ease of the application of molecular techniques for its genetic manipulation. Therefore, this fungus provides a highly suitable system to study basic biological processes that are relevant for many other higher eukaryotes including man.
   • Download Results : FASTA, CSV
   • Data from EBI
   
2. Schizosaccharomyces pombe (Fission Yeast)
   S. pombe was the sixth organism with a nucleus to have its genome sequenced, following humans, the nematode worm, the fruit fly, mustard weed, and budding yeast. Of these completed eukaryotic organisms, S. pombe has the smallest and most compact genome. It contains 13.8 million base pairs distributed among 3 chromosomes and 4,824 genes. This is the lowest number of protein-coding genes yet identified in a free-living eukaryotic cell. It is also substantially lower than the 5,600 genes found in Saccharomyces cerevisiae. Researchers have identified fifty genes of S. pombe associated with human diseases-including cystic fibrosis, hereditary deafness, and diabetes. Researchers state that the largest group of human disease-related genes are those implicated in cancer. There are 23 such genes, and they are involved in DNA damage and repair, checkpoint controls, and the cell cycle, all processes involved in maintaining genomic stability.
   • Download Results : FASTA, CSV
   • Data from EBI
   

* CSV stands for Comma Separated Values which is a file format that is compatible with most spreadsheet programs (e.g. Excel). Each line in the file contains the predictions for one protein, the probabilities for the predictions are separated by commas.